Refrain: Prefixes precede and advance the meaning. Without them there, their sense would be misleading. So if prefixation is what you're seeking Disconnect your confusion 'cause I'm intervening. Prefixes change the meaning of everything Making charged -- supercharged; lasting -- everlasting... Refrain Bicycle, bi-level, bilingual, biplane That's when you have two of the same... Refrain Defuse, disinfect, deforest, disobey De- and dis- make opposites of what you say...