Developing autoimmune diseases Tissue injury caused by an apparent Immunologic reaction of the host With it's own tissue Tissue injury Gastrointestinal bleeding Agonizing anemia Transplacental infection From a carrier mother Chronic liver disease Acute fulminating hepatitis Inflammation, atrophy, anemia Anomalous condition horror Autotoxicus Self destructive process immunological Reaction Arising through somatic mutation Mutant cells will be normally destroyed Renal transplantation is recommended to the patients With end stage renal disease Post transplantation follow up describes many complications