Upon Injection of antigen into the Skin A local anaphilactic Reaction will occur A wheal and flare Reaction Allergy to a wide Variety of Antigens The local Increase in vascular Permeability Use of Tracer dyes such as Evans blue dye The binds to albumin in the Blood Blood vassels exhibit increased permeability Cutaneous Anaphilaxis Ahhh- Mechanisms of Tissue Active Cutaneous Anaphilaxis-Swelling and redness Passive Cutaneous Anaphilaxis-Specific types of Antibody Passive Cutaneous Anaphilaxis-Bluing of the Skin Anaphilaxis The anaphilactic reactions are mediated By substances such as Histamine Since they are quickly inativated By tissues and plasma